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  • Innoprot
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      • GPCR Cell Lines

HiTSeeker ADRB2 Cell Line (Adrenergic Receptor beta2)

Reference: P30125

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Data Sheet

Each vial of HiTSeeker ADRB2 contains 3 million of HEK293 cells stably expressing human Adrenergic beta-2 Receptor (ADRB2) with no tag. We offer this cell line as a “stable cell line” but we are now also offering vials of division-arrested cells (DA cells) in order to perform a small number of assays. Each vial of these DA cells contains 2.5 million cells, an enough number of cells to perform a complete experiment in a 96 well-plate or 384 well-plate.

Innoprot HiTSeeker ADRB2 Cell Line has been designed to assay compounds or analyze their capability to modulate Adrenergic beta-2 Receptor. When an agonist binds to the ADRB2 a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (cAMP). This cell line has been validated measuring cAMP increase in the cytosol. The high reproducibility of this assay allows monitoring ADRB2 receptor activation process in High Throughput Screening.

Materials Provided

  • P30125: 2 vials of 3 million stably transfected HEK293 Cells expressing ADRB2
  • P30125-DA: 1 vial with 2.5 million Division Arrested HEK293 Cells expressing ADRB2 (READY TO USE)

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